Overview of Selected Chemical Compounds and Intermediates

Overview of Selected Chemical Compounds and Intermediates

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1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is certainly an impurity associated with bortezomib, a proteasome inhibitor used in the treatment method of a number of myeloma. Its synthesis or examine is critical for making certain the purity and safety of the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor from the synthesis of abiraterone acetate, a drug Utilized in the treatment of prostate most cancers by inhibiting androgen creation.
Imatinib Intermediate (CAS NO. 152460-10-one): A crucial compound in the synthesis of imatinib, a drug that targets unique different types of cancer, including Long-term myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats several cancers like breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): They're intermediates during the synthesis of gemcitabine, an anti-cancer drug. Their analyze is crucial for optimizing the creation system and making certain significant purity.
Lapatinib Intermediate (CAS NO. 231278-84-5): Lapatinib is applied to take care of breast cancer, and these intermediates are involved with its manufacturing.
Fulvestrant Intermediates: Fulvestrant can be an estrogen receptor antagonist Employed in the treatment method of breast most cancers. Various intermediates help in the synthesis of this drug.
Paclitaxel Aspect Chain Acid (CAS NO. 949023-sixteen-nine): This intermediate is Employed in the synthesis of paclitaxel, a chemotherapy GeMcitabineInterMediate9 drug efficient in dealing with cancers for instance ovarian, breast, and lung most cancers.
three. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug used in the remedy of colorectal cancer and smaller mobile lung most cancers.
three-Amino-one-hydroxyadamantane (CAS 702-eighty two-nine): This compound is involved in the synthesis of adamantane derivatives, which have a variety of apps, such as antiviral Homes.
Vildagliptin Intermediates: Utilized in the manufacture of vildagliptin, an oral drug for form two diabetic issues that inhibits the enzyme DPP-four to control blood sugar concentrations.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-1): This compound is involved with the synthesis of assorted gluconic acid derivatives, which can be Utilized in foodstuff, pharmaceutical, and industrial apps.
Canagliflozin Intermediate two: 5'-dibenzoate A precursor in the synthesis of canagliflozin, a medication utilized to manage kind two diabetic issues by inhibiting sodium-glucose co-transporter two (SGLT2).